High-quality targeted analysis, suspect-screening and non-target screening approaches, supported by advanced modelling and data analysis pipelines, are applied for exposure assessment, human biomonitoring, effect-directed analysis, and metabolomics/lipidomics purposes, that are closely interlinked with the section Environmental Health and Toxicology. We are specialized in multiple analytical techniques (including LC-MS/MS, UPLC-HR-qTOFMS, LCxLC-HR-qTOFMS, GC-MS, GC-HR-qTOFMS, GCxGC-HR-qTOFMS,MALDI-TOF) with different inlet/ionisation techniques (EI, ESI, APCI, APPI, IonBooster, DirectProbe, AP-MALDI, pyrolysis), and numerous other high quality instruments, such as an in house developed fraction collector for 96/384 microtiter plates (Fractiomate™) to enable high throughput testing for the identification of emerging contaminants and unknown metabolites. We complement these analytical methodologies by developing and implementing a broad range of advanced modelling, machine learning and cheminformatics tools. Our expertise and research output is integrated in student education programs at BSc, MSc, and PhD level and make an important contribution to the knowledge needed for informed environmental governance of the most pressing environmental pollution issues.
Chemistry for Environment & Health
A-LIFE section Chemistry for Environment & Health performs world-leading research to develop analytical chemistry and computational methodologies for the prioritisation and identification of environmental and health issues of emerging concern.